I have my family room and master bedroom separated by one wall, and both sides of that wall has all of the A/V connections for the two rooms.  Am I nuts to think that I can’t have one HTPC run both rooms?  I would only use the HTPC in one room at a time and therefore only need one remote.  I’m thinking the only thing I would need to do is run 2 video cards (or one with dual HDMI) to send both the audio and video to each room.  Am I missing something?